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Am J Trop Med Hyg ; 103(4): 1597-1599, 2020 10.
Article in English | MEDLINE | ID: covidwho-725412

ABSTRACT

COVID-19, designated as SARS-CoV-2, has caused millions of infections worldwide, including in patients with concomitant infections. Here, we report two unusual cases of patients with triple infections of SARS-CoV-2, Mycobacterium tuberculosis, and HIV. Both cases were confirmed through microbiological and immunological studies. The acute respiratory phase in both patients was treated with supplemental oxygen. Antituberculosis and antiretroviral therapies were started simultaneously. In 2 weeks, both patients demonstrated clinical improvement and recovery from COVID-19. Our findings suggest that even in cases of triple infection, clinical management together with respiratory therapy contributes to patient survival.


Subject(s)
Antitubercular Agents/therapeutic use , Antiviral Agents/therapeutic use , Coronavirus Infections/therapy , HIV Infections/therapy , Heparin/therapeutic use , Hydroxychloroquine/therapeutic use , Pneumonia, Viral/therapy , Tuberculosis, Pulmonary/therapy , Adult , Betacoronavirus/pathogenicity , COVID-19 , Coinfection , Convalescence , Coronavirus Infections/immunology , Coronavirus Infections/microbiology , Coronavirus Infections/virology , HIV/pathogenicity , HIV Infections/immunology , HIV Infections/microbiology , HIV Infections/virology , Humans , Male , Middle Aged , Mycobacterium tuberculosis/pathogenicity , Pandemics , Pneumonia, Viral/immunology , Pneumonia, Viral/microbiology , Pneumonia, Viral/virology , Positive-Pressure Respiration/methods , SARS-CoV-2 , Tuberculosis, Pulmonary/immunology , Tuberculosis, Pulmonary/microbiology , Tuberculosis, Pulmonary/virology
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